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Evaluating Moringa-Derived Bioactive Compounds as Natural Alternatives for Oral Health: Inhibition of S. mutans Growth
​

Sohyun Park
Chadwick International, Incheon, South Korea
​​Publication date: November 20, 2025
​DOI: http://doi.org/10.34614/JIYRC2025II35
ABSTRACT 
This study investigated the antibacterial effects of Moringa Oleifera extract on Streptococcus mutans (S. mutans), a primary cause of dental plaque. S. mutans forms biofilms and produces acids that promote enamel demineralization, while conventional oral care products often fail to fully inhibit its growth. To assess Moringa’s effectiveness as a natural oral-care alternative, a 0.02% Moringa solution was prepared and tested against S. mutans cultures in 96-well plates. Bacterial growth was measured on Days 0 and 7 using varying Moringa volumes (0-100 µL) and a 10µL S. mutans inoculum. The strongest inhibitory effect was observed at 70 to 100 µL, while the optimal condition for measurable growth suppression occurred with 10 µL of S. mutans. These findings highlight Moringa’s potential as a natural antibacterial agent for oral health applications.

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  • Information
    • Editorial Board
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  • Articles
    • 2024
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  • Guide for authors
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    • Submission system
  • Become a reviewer